Russian-Swiss development · since 2019
SYNTHESIT
The Synthesit mineral is obtained through low-energy nuclear reactions (LENR) using its own proprietary method. Its effects reach far beyond ordinary iron — as research in nine countries shows.
Studied in 9 countriesSynthesit and blood
Iron is the basis of haemoglobin — the protein in red blood cells that delivers oxygen to every cell of the body. Synthesit is a special form of iron, and studies show its effect on blood goes beyond simply replenishing iron.
More than iron
Synthesit works in micro-doses. Ordinary iron is needed for haemoglobin and oxygen transport — while studies of Synthesit describe effects far beyond that, from blood formation to genes linked with longevity.
Iron citrate is a familiar, well-tolerated form. The only restriction is individual iron intolerance, which is extremely rare.
A 2019 discovery
×2.45undifferentiated bone marrow cells
The first study of Synthesit was carried out at the Federal Research Institute of Medical Primatology (Sochi). In mice that received the mineral, the number of undifferentiated (stem) cells in the bone marrow rose from 2.2 to 5.4 — 2.45 times.
All differences are statistically significant. Each row has its own scale.
Bulgin D. V., Karabanov V. A., Karabanov R. V. — Research Institute of Medical Primatology, 2019. Journal version — Edelweiss Applied Science and Technology, 2024. DOI 10.55214/25768484.v8i4.1602
Control
SynthesitTechnology
The mineral is obtained in the laboratory through low-energy nuclear reactions (LENR) using its own method — stable elements give rise to iron with an isotopic signature of its own.
NIC SYNTHESTECH laboratory founded in SochiSynthesit obtained for the first time; presented at Club Suisse de la Presse, GenevaFirst stem cell report — Research Institute of Medical PrimatologySynthesit Swiss SA founded in GenevaPaper in Frontiers in Nutrition by scientists from four countriesMakrolife Biotech (Germany) studies its effect on human immune cellsResearch
The mineral is studied in cells, in animals and in the clinic. The key paper is indexed in PubMed, the database of the US National Library of Medicine.
Animal study · 30 days
Higher maximal oxygen uptake and new mitochondria in muscle; activation of PGC-1α, SIRT1 and NRF-2.
HungaryHungarian University of Sport Science JapanWaseda University · University of Tokyo ChinaNingbo University SwitzerlandSynthesit Swiss SAMakrolife Biotech · Germany
Expression of 40 genes in human macrophages. Synthesit shifted the cells toward the restorative M2 type.
Prof. O. Sh. Oynotkinova
Patients with colorectal cancer and lymphoproliferative diseases took Synthesit before, during and after their chemotherapy courses.
Moscow State University and partners
Thirty days of intake — and clear changes in blood properties and antioxidant defence.
Research Institute of Medical Primatology · Russian Academy of Sciences
Ageing rhesus macaques showed lower blood glucose and cholesterol; in cells, activity of the Klotho gene increased.
Results are presented as scientific information and are not a promise of any therapeutic effect. Some of the studies involved company specialists. Supplements with Synthesit are not medicines.
Makrolife Biotech · Germany
In 2025 the German biotechnology company Makrolife Biotech (a SYDROS division) studied how Synthesit changes gene activity in primary human macrophages — the cells that govern inflammation and tissue repair. The analysis was performed by RT-qPCR in the S2 laboratory of the Bruchsal Technology Park.
| IL10 | +88.4% | |
|---|---|---|
| ARG1 | +82% | |
| TGFB1 | +75% | |
| SOCS3 | +63% | |
| CD163 | +56% | |
| IL1RN | +56% | |
| MRC1 | +47% | |
| CX3CR1 | +38% | |
| PPARG | +26% | |
| STAT6 | +15% |
| HMOX1 | +88% | |
|---|---|---|
| PGC1A | +75% | |
| CPT1A | +60% | |
| NRF1 | +58% | |
| SIRT1 | +47% | |
| UCP2 | +45% | |
| PDK4 | +40% | |
| ACACA | +36% | |
| AMPK | +34% | |
| AKT1 | +28% |
| GLUT1 | +66% | |
|---|---|---|
| IGF1 | +55% | |
| IL1RN | +53% | |
| IRS2 | +50% | |
| PPARG | +45% | |
| AKT2 | +44% | |
| LEPR | +40% | |
| GLUT4 | +38% | |
| SOCS3 | +25% | |
| TNF | −30% |
| HMOX1 | +100% | |
|---|---|---|
| NRF2 | +88.4% | |
| FOXO3 | +75% | |
| SOD2 | +64.8% | |
| GPX1 | +51.6% | |
| TXN | +51.6% | |
| GCLC | +41.4% | |
| SIRT1 | +28.1% | |
| CAT | +23.1% | |
| PON1 | +14.9% |
In vitro study on human cells commissioned by NIC SYNTHESTECH. Expression change versus control, ΔΔCt method, normalised to β-actin.
Full Makrolife Biotech report (PDF) ↗Documents and facts
Real photographs, laboratory reports, certificates and publications — everything this story is based on.
Worldwide
Universities, clinics and independent laboratories in nine countries.
123456789 USAIndependent laboratory analyses
Russian-Swiss foundation
Synthesit was born in Russia and is researched from Switzerland. All three companies are united by the developer of the technology.
Geneva · Switzerland
The company through which international research on the mineral is conducted — with universities and laboratories in Europe and Asia, including the Frontiers in Nutrition study.
UID CHE-354.745.143
Swiss commercial register ↗
Certificate of quality for SYNTHESIT LTD products (PDF) ↗Roman KarabanovDirector and developer of the technology
Sochi · Russia
Research laboratory
The laboratory where Synthesit was first obtained in 2019, and where the LENR technology is developed.
Manufacturer
The main manufacturer of supplements with the Synthesit mineral.
Champions
World-class athletes on what Synthesit gave them.
Argentina · Dakar RallyLuciano BenavidesDakar 2026 winner, 2023 World Rally-Raid Champion
It was key to my recovery and to winning the Dakar!
Japan · triathlonMaiko OtaIronman World Championship, KONA
My overall performance has improved compared with previous seasons.
Russia · MMAAlexander ShlemenkoThree-time Bellator champion
It's as if I had powered myself up three times over.
Russia · high jumpKristina KorolevaRussian champion
Synthesit helped me handle heavy training loads and recover faster after competitions.
Personal experience of the athletes. Results may vary from person to person.
Video interviews
The Synthesit channel holds more than five hundred video interviews: people from different countries talk on camera about their experience with Synthesit. Here are a few from Europe and the USA.
500+video reviews on the Synthesit channel
Personal experience. Results may vary from person to person.
Exhibitions
From 2019 to 2023 Synthesit was presented at industry exhibitions in Europe, the Middle East, North America and Asia.
8–10 November 2023 · Shanghai World Expo Exhibition & Convention Center
GenevaVitafoods Europe
DubaiDUPHAT
PhiladelphiaNatural Products Expo East
ParisNatexpo
CologneFIBO
TokyoSPORTEC
Las VegasOlympia ExpoSynthesit worldwide
People in many countries have been taking Synthesit for more than five years. The feedback is astonishing: many of its positive effects are still being studied, yet you can feel them for yourself today.
Contact the official representative in your country — they will select a Synthesit formula developed for your needs, and you will receive genuine Synthesit.
Supplements with Synthesit are not medicines.
